Akineton: Uses, Dosage, Indications, and Side Effects

Dosage form:

Oral tablets (Prolonged-release) 4mg, 2mg

Active ingredient:

Biperiden hydrochloride

What is Akineton used for?

A prescription-only drug Akineton; is primarily used to treat all forms of Parkinson’s disease. Other therapeutic indications include

  • Drug-induced extrapyramidal symptoms
  • Excito-motor phenomena
  • Akinesia
  • Rigidity
  • Akathisia
  • Acute dystonia

Akineton is also available in 5mg/ml ampules.

Contraindications

  • Hypersensitivity
  • Narrow-angle glaucoma
  • Megacolon

Akineton Drug Interactions

  • Levodopa
  • Carbidopa
  • Metoclopramide
  • Pethidine

Akineton Side effects

Side effects are more likely to develop at the start of therapy and when the dosage is increased too rapidly.

Patients with symptoms of a cerebral deficit are more likely to have central excitation effects, which may need a dose reduction.

  • Excitement
  • Agitation
  • Fear
  • Confusion
  • Delirious syndromes
  • Hallucinations
  • Sleeplessness
  • Nervousness
  • Euphoria
  • Fatigue
  • Dizziness
  • Disturbance of memory
  • Headache
  • Dyskinesia
  • Ataxia and speaking disorder
  • Increased disposition to cerebral seizures
  • Convulsions
  • Disturbance of accommodation
  • Mydriasis
  • Photosensitivity
  • Closed-angle glaucoma might occur (controlling of intraocular pressure)
  • Tachycardia
  • Bradycardia
  • Dryness of mouth
  • Nausea
  • Constipation
  • Reduced perspiration
  • Allergic rash
  • Muscle twitching
  • Voiding disorders
  • Urinary retention
  • Drowsiness
Headache

How do you use Akineton?

Treatment usually starts with a 2mg per day dose and then the dosage gradually increases. The maximum daily dose should not exceed 16mg per day. Always follow your doctor’s or pharmacist’s instructions when using this medication. If you’re not sure, ask your doctor or pharmacist.

This medication must be dosed on an individual basis.

Treatment should begin with the lowest dose feasible and gradually rise to the level that is most effective for you.

References

https://mri.cts-mrp.eu/Human/Downloads/AT_H_0521_002_FinalSPC.pdf
https://mri.cts-mrp.eu/human/downloads/AT_H_0521_001_FinalPL.pdf
https://www.drugs.com/pro/akineton.html

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