Akineton: Uses, Dosage, Indications, and Side Effects


Dosage form: Oral tablets (Prolonged-release) 4mg, 2mg Active ingredient: Biperiden hydrochloride What is Akineton used for? A prescription-only drug Akineton; is primarily used to treat all forms of Parkinson’s disease. Other therapeutic indications include Drug-induced extrapyramidal symptoms Excito-motor phenomena Akinesia Rigidity Akathisia Acute dystonia Akineton is also available in 5mg/ml ampules. Contraindications Hypersensitivity Narrow-angle glaucoma … Read more

Biperiden: Uses, Side Effects and Mechanism of Action


What is Biperiden? A cholinergic antagonist drug biperiden is used to treat Parkinsonism. Biperiden Hydrochloride Biperiden Hydrochloride is the salt from the drug Biperiden. Tablet dosage forms of it include the drug in this chemical form. A central and peripheral nerve system muscarinic antagonist. Arteriosclerotic, idiopathic, and postencephalitic parkinsonism have all been treated with it. … Read more

Mesnex: Uses, Side Effects, Dosage Forms, and Manufacturers


Mesnex is a chemo protectant that may be taken as injections or pills. It has also been studied as a mucolytic agent in experimental trials. What is Mesnex used for? It is used as a preventative measure to reduce the risk of ifosfamide-induced hemorrhagic cystitis. Mesnex Dosage Forms 1 g Multidose Vial, and 100 mg/mL … Read more

Mesna (chemoprotectant): Contraindications, Side Effects, Uses, and Brand Names


A synthetic sulfhydryl compound Mesna; is a chemo-protective agent used to prevent ifosfamide-induced hemorrhagic cystitis. It can be given intravenously or orally. The drug is rapidly oxidized to mesna disulfide, which is its main metabolite (dimesna). In the kidney, dimesna is reduced to a free thiol, which interacts with ifosfamide metabolites and causes their detoxification. … Read more

Pentamidine: Uses, Mechanism of Action, Side Effects, and Contraindications


What is Pentamidine? The drug Pentamidine is broadly classified under anti-protozoal drugs. Several diamidine compounds have trypanocidal action, including pentamidine. In the treatment of visceral leishmaniasis, pentamidine isethionate is utilized instead of sodium stibogluconate. It can also be used to treat early trypanosomiasis. Pentamidine Mechanism of Action The precise mechanism has yet to be discovered. … Read more

Eflornithine: Mechanism of Action, Uses, Side effects, and Contraindications


Difluoromethylornithine DFMO which is now commonly known as Eflornithine shows clinical efficacy against Pneumocystis pneumonia (PCP) and West African trypanosomiasis. The drug was initially designed to be used as an anticancer agent, but it proved to be unproductive later. African sleeping sickness, which is also known as Human African trypanosomiasis, is a parasite infection transmitted … Read more

Sulfasalazine: Side Effects, Interactions, and Uses


What is Sulfasalazine? A prodrug: sulfasalazine, is used in the treatment of chronic inflammatory bowel disease and to treat rheumatoid arthritis as second-line therapy. It’s composed of sulfapyridine and 5-aminosalicylic acid (5-ASA) connected by an azo bond, which is broken by bacteria in the distal ileum and colon to release the active ingredients. In the … Read more

Azulfidine: Uses, Active ingredient, and Warnings


What is Azulfidine? Azulfidine is a brand name of the drug, containing Sulfasalazine as an active ingredient. Sulfasalazine is known to possess anti-inflammatory activity and is thus used to treat Rheumatoid arthritis. It is a prescription-only medication. Generic name Sulfasalazine (Drug class: Anti-inflammatory, Disease-modifying antirheumatic drugs (DMARDs), 5-Aminosalicylic acid derivatives) Sulfasalazine (Azulfidine) available dosage forms … Read more

Lampit (Nifurtimox Tablets): Uses, Contraindications, and Side Effects


What is LAMPIT and why it is used? Lampit is nifurtimox-containing tablets. Nifurtimox is classified as an antiprotozoal drug used to treat Chagas disease which is caused by Trypanosoma cruzi. Active Ingredient Active ingredient of Lampit is Nifurtimox. LAMPIT Contraindications Patients who have a known hypersensitivity to nifurtimox or any of the excipients in LAMPIT, … Read more