Sulfasalazine: Side Effects, Interactions, and Uses


What is Sulfasalazine? A prodrug: sulfasalazine, is used in the treatment of chronic inflammatory bowel disease and to treat rheumatoid arthritis as second-line therapy. It’s composed of sulfapyridine and 5-aminosalicylic acid (5-ASA) connected by an azo bond, which is broken by bacteria in the distal ileum and colon to release the active ingredients. In the … Read more