Cancer

In Alzheimer’s Disease Brain Cell Death is Linked to Damage in Skeleton Protecting Those Cells

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Alzheimer’s Disease

Researchers have discovered that the skeleton surrounding the nucleus of brain cells is dysfunctional in Alzheimer’s disease patients, which could lead to neuronal death. The study, “Lamin Dysfunction Mediates Neurodegeneration in Tauopathies,” was published in Current Biology. The lamin nucleoskeleton that surrounds the nucleus of cells is important in the maintenance of nuclear organization, primarily … Read more

Could you spot the early signs of Dementia – 3 symptoms you should not ignore

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early signs of Dementia

Will you be tuning in to Channel 4’s new documentary, Dementiaville? The three-part series, starting June 4th, will explore groundbreaking new approaches to treatment at Poppy Lodge care home, as well as shine a light on the condition. Living with dementia doesn’t just affect the person who’s been diagnosed, it impacts the whole family, and … Read more

Unmasking Paraneoplastic Pemphigus: Skin Disorder and Cancer Connection

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Unmasking Paraneoplastic Pemphigus

Paraneoplastic Pemphigus, or PNP, is a rare autoimmune blistering disorder that is associated with cancer. PNP affects about one in 20 million people worldwide and has a high mortality rate. People with PNP experience various skin and mucosal lesions, as well as respiratory and systemic complications. What types of cancer are associated with Paraneoplastic Pemphigus? … Read more

Understanding the Link Between Myelodysplastic Syndrome and Railroads

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Understanding the Link Between Myelodysplastic Syndrome and Railroads

Myelodysplastic Syndrome (MDS) is a complex and potentially life-threatening condition characterized by abnormal development of blood cells in the bone marrow. Over the years, research has uncovered a possible link between MDS and exposure to certain occupational hazards, including railroads. While the exact relationship is still being explored, studies have suggested that individuals who have … Read more

Miltefosine: Uses, Contraindications, Side Effects, and Mechanism of Action

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Miltefosine

Initially developed as an anti-cancer drug, Miltefosine is chemically a phosphorylcholine ester of hexadecanol. It is an anti-leishmanial drug. Miltefosine is the first medicine to be given orally as a membrane-active alkyl phospholipid to treat “Cutaneous and Visceral leishmaniasis”. It is an oral medicine that, unlike earlier traditional therapy such as pentavalent antimonial drugs, amphotericin … Read more