A comparison of Invokana vs Jardiance is provided here. While both drugs are used for glycemic control in patients with type II diabetes, Jardiance also helps in reducing the risk of cardiovascular diseases in patients and can be eliminated through both kidneys and liver while Invokana is excreted mainly through the kidneys. Both of these are two commonly prescribed drugs that belong to a class known as sodium-glucose cotransporter-2 (SGLT2) inhibitors. In this article, we will delve into the similarities and differences between Invokana and Jardiance, highlighting their mechanisms of action, side effects, efficacy, and more.
What is Invokana?
Invokana, also known by its generic name canagliflozin, is an oral medication used to control blood sugar levels in adults with type 2 diabetes. It works by inhibiting SGLT2 receptors in the kidneys, reducing glucose reabsorption and increasing glucose excretion through urine.
What is Jardiance?
Jardiance, with the generic name empagliflozin, is another SGLT2 inhibitor that helps manage blood sugar levels in individuals with type 2 diabetes. Similar to Invokana, it reduces glucose reabsorption in the kidneys and promotes glucose elimination through urine.
Invokana vs Jardiance: Mechanism of Action
Invokana (generic name: canagliflozin) and Jardiance (generic name: empagliflozin) work by inhibiting the SGLT2 protein in the kidneys. This protein is responsible for reabsorbing glucose back into the bloodstream. By inhibiting SGLT2, both medications increase the excretion of glucose through urine, resulting in lower blood sugar levels.
Effectiveness in Lowering Blood Sugar
Both Invokana and Jardiance have demonstrated efficacy in lowering blood sugar levels in patients with type 2 diabetes. Clinical studies have shown that these medications can effectively reduce HbA1c levels, which is a long-term marker of blood glucose control.
Invokana vs Jardiance: Safety Profile
When it comes to the safety profile, both medications have been generally well-tolerated by patients. However, there are some differences worth noting. Invokana has been associated with an increased risk of genital infections and urinary tract infections. Jardiance, on the other hand, has shown a reduced risk of cardiovascular events and improved renal outcomes in patients with established cardiovascular disease.
Cardiovascular Benefits
While both Invokana and Jardiance have shown cardiovascular benefits, Jardiance has been extensively studied in this area. Clinical trials have demonstrated a reduction in major adverse cardiovascular events, such as heart attacks and strokes, in patients taking Jardiance. Invokana has also shown some cardiovascular benefits but to a lesser extent.
Side Effects: Invokana vs Jardiance
Invokana Side Effects:
- Genital Infections: Invokana has been associated with an increased risk of genital infections, such as yeast infections in both males and females. Symptoms may include itching, redness, swelling, and discharge.
- Urinary Tract Infections: Another common side effect of Invokana is urinary tract infections (UTIs). Symptoms may include frequent urination, pain or burning sensation during urination, cloudy urine, and abdominal pain.
- Increased Urination: Invokana works by increasing glucose excretion through urine, which can lead to increased frequency of urination.
- Decreased Blood Pressure: Invokana may cause a decrease in blood pressure, leading to symptoms such as dizziness, lightheadedness, or fainting. It is important to stand up slowly from a sitting or lying position to minimize the risk of falls.
Jardiance Side Effects:
- Urinary Tract Infections: Similar to Invokana, Jardiance can also increase the risk of urinary tract infections. Symptoms and effects are similar to those mentioned for Invokana.
- Yeast Infections: Jardiance may also increase the risk of yeast infections in both males and females. Symptoms may include itching, redness, soreness, and discharge.
- Increased Urination: Jardiance, like Invokana, increases the excretion of glucose through urine, resulting in increased urination.
- Decreased Blood Pressure: Jardiance can cause a decrease in blood pressure, leading to symptoms such as dizziness, lightheadedness, or fainting.
It is important to note that the side effects mentioned above are not exhaustive, and individual experiences may vary. It is recommended to consult with your healthcare provider for a comprehensive understanding of the potential side effects and how to manage them effectively.
Invokana vs Jardiance: Dosage and Administration
When comparing the usage of Invokana and Jardiance, there are several factors to consider. Both medications are taken orally and are typically prescribed as a once-daily dosage. However, there are some differences in their specific usage and administration.
Invokana (canagliflozin) is available in tablet form and is usually taken in the morning before breakfast. It is important to follow the dosage instructions provided by your healthcare professional and take the medication at the same time each day for consistency. Invokana can be taken with or without food, but it is generally recommended to take it before a meal to enhance its effectiveness.
On the other hand, Jardiance (empagliflozin) is also available in tablet form and is usually taken once daily. However, unlike Invokana, Jardiance can be taken with or without food. It is essential to follow the prescribed dosage and timing instructions provided by your healthcare provider.
In terms of dosages, both Invokana and Jardiance have different strengths available. The specific dosage prescribed to an individual will depend on various factors such as their medical history, kidney function, and response to treatment. Your healthcare provider will determine the most appropriate dosage for you based on your unique circumstances.
It is crucial to take Invokana and Jardiance as prescribed by your healthcare professional. Adhering to the prescribed dosage and timing is essential for optimal effectiveness and management of your blood sugar levels. If you have any questions or concerns about the usage of these medications, it is important to consult with your healthcare provider or pharmacist for guidance.
Drug Interactions
Invokana and Jardiance may interact with certain medications, including diuretics, insulin, and other drugs that lower blood sugar levels. It is vital to inform your healthcare provider about all the medications you are currently taking to avoid any potential drug interactions.
Cost Comparison of Invokana and Jardiance
When it comes to the cost, the prices of Invokana and Jardiance can vary depending on factors such as your insurance coverage and location. It is recommended to check with your healthcare provider or pharmacist for the most accurate and up-to-date pricing information. For a rough estimate, both drugs cost upwards of $600 for a 30 day supply.
Patient Experiences and Preferences
Individual experiences and preferences may vary when it comes to choosing between Invokana and Jardiance. Some patients may find one medication more effective or tolerable than the other. It is important to discuss your specific needs and preferences with your healthcare provider to determine the most suitable option for you.
Invokana vs Jardiance: The Final Verdict
In conclusion, both Invokana and Jardiance are effective medications for managing blood sugar levels in patients with type 2 diabetes. They work by inhibiting the SGLT2 protein in the kidneys, leading to increased glucose excretion. While Invokana has been associated with an increased risk of genital and urinary tract infections, Jardiance has shown cardiovascular benefits and improved renal outcomes. It is crucial to consult your healthcare provider to determine the most appropriate medication for your specific needs.
[youtube https://www.youtube.com/watch?v=ZpEhBfqVvzQ&w=560&h=315]FAQs
Is Jardiance and Invokana the same?
Jardiance (empagliflozin) and Invokana (canagliflozin) both belong to the same class of medications known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. While they have similar mechanisms of action and are used to manage blood sugar levels in individuals with type 2 diabetes, they are different medications with their own unique properties and characteristics.
What drug is better than Jardiance?
The effectiveness and suitability of a medication can vary from person to person. There are several SGLT2 inhibitors available that may be considered as alternatives to Jardiance, such as Invokana (canagliflozin) and Farxiga (dapagliflozin). The choice of medication depends on individual factors, including medical history, treatment goals, and healthcare provider’s recommendation. It is important to consult with your healthcare provider to determine the most suitable option for you.
Which is better empagliflozin vs canagliflozin?
The comparison between empagliflozin (Jardiance) and canagliflozin (Invokana) depends on individual factors and preferences. Both medications are effective in managing blood sugar levels and have shown cardiovascular and kidney benefits. The choice between the two should be made in consultation with your healthcare provider, taking into account factors such as medical history, potential drug interactions, side effects, and treatment goals.
What can replace Invokana?
There are other SGLT2 inhibitors available that can be considered as alternatives to Invokana (canagliflozin). Some examples include Jardiance (empagliflozin), Farxiga (dapagliflozin), and Steglatro (ertugliflozin). The choice of medication depends on various factors, and it is important to discuss alternatives with your healthcare provider to determine the most appropriate replacement based on your individual needs.
What is equal to Jardiance?
Jardiance (empagliflozin) is a unique medication in its class of SGLT2 inhibitors. While there are other SGLT2 inhibitors available, such as Invokana (canagliflozin) and Farxiga (dapagliflozin), they are not exactly equal to Jardiance. Each medication has its own specific characteristics, effectiveness, and safety profile. It is important to consult with your healthcare provider to determine the most suitable medication for your diabetes management.
Is Invokana a good drug for diabetes?
Invokana (canagliflozin) is considered an effective medication for managing blood sugar levels in individuals with type 2 diabetes. It has shown efficacy in reducing HbA1c levels, promoting weight loss, and providing cardiovascular and kidney benefits. However, the suitability of Invokana as a treatment option depends on individual factors and should be determined in consultation with a healthcare provider.
Is Jardiance good or bad for kidneys?
Jardiance (empagliflozin) has been shown to have renal benefits and can help slow the progression of diabetic kidney disease. It reduces the risk of kidney failure and has been associated with positive outcomes in clinical trials. However, as with any medication, it is important to discuss your kidney health and individual circumstances with your healthcare provider to determine the appropriateness of Jardiance for your specific situation.
Does Jardiance help kidneys?
Yes, Jardiance (empagliflozin) has demonstrated kidney-protective effects in individuals with type 2 diabetes. Clinical trials have shown that it can help slow the progression of diabetic kidney disease and reduce the risk of kidney failure. It is important to consult with your healthcare provider to assess your kidney health and determine the most suitable treatment approach for you.
Is there a cheaper substitute for Jardiance?
When it comes to medication costs, it can vary depending on factors such as insurance coverage, pharmacy pricing, and availability of generic options. There may be alternative SGLT2 inhibitors available at different price points, such as Invokana (canagliflozin) or Farxiga (dapagliflozin), which could be considered as potential substitutes for Jardiance. However, it is important to consult with your healthcare provider and pharmacist to discuss the most cost-effective options based on your specific circumstances.
Which SGLT2 is the best?
The choice of the best SGLT2 inhibitor depends on various factors, including individual medical history, treatment goals, potential drug interactions, and personal preferences. Different SGLT2 inhibitors, such as Jardiance (empagliflozin), Invokana (canagliflozin), and Farxiga (dapagliflozin), have their own unique characteristics and benefits. It is important to consult with your healthcare provider to determine the most suitable option for your specific needs.
Can you take Invokana and Jardiance together?
The concomitant use of Invokana (canagliflozin) and Jardiance (empagliflozin) is generally not recommended due to the similar mechanism of action and potential overlapping effects. Combining these medications may increase the risk of side effects and complications. It is crucial to follow your healthcare provider’s instructions and take only the prescribed medication for your diabetes management.
Is Jardiance better than glimepiride?
Jardiance (empagliflozin) and glimepiride belong to different classes of diabetes medications with distinct mechanisms of action. While Jardiance is an SGLT2 inhibitor, glimepiride is a sulfonylurea. The choice between these medications depends on individual factors, including medical history, treatment goals, and potential side effects. It is important to consult with your healthcare provider to determine the most appropriate medication for your specific needs.
Is Invokana safe for kidneys?
Invokana (canagliflozin) has shown renal benefits and has been associated with a reduction in the risk of kidney failure in individuals with type 2 diabetes. However, as with any medication, it is important to consider individual factors, such as kidney function and medical history, and consult with your healthcare provider to ensure the safe and appropriate use of Invokana in your specific situation.
Is Invokana safe now?
Invokana (canagliflozin) has been approved by regulatory authorities for the management of type 2 diabetes. Like any medication, it has potential side effects and considerations that need to be evaluated in consultation with your healthcare provider. The safety and suitability of Invokana depend on individual factors, and it is important to discuss your medical history and any concerns with your healthcare provider.
Who should not take Invokana?
Invokana (canagliflozin) may not be suitable for everyone. Individuals with severe kidney impairment, a history of serious hypersensitivity reactions to canagliflozin, or those on dialysis should avoid taking Invokana. It is important to inform your healthcare provider about your medical history and any existing conditions to determine the appropriateness of Invokana as a treatment option for you.
References
- National Institutes of Health (NIH) – www.nih.gov
- American Diabetes Association (ADA) – www.diabetes.org
- Mayo Clinic – www.mayoclinic.org
