Category:

Depression

Viibryd vs Trintellix: The Ultimate Face-off in Treating Depression

by Dr Mahmood Rehan July 24, 2023

written by Dr Mahmood Rehan

Let's look into the phenomenon of Viibryd vs Trintellix. In a few words, the main difference between both is that Viibryd is a selective serotonin reuptake inhibitor (SSRI) and partial agonist of serotonin receptors, while Trintellix is a serotonin modulator and stimulator, leading to different approaches in treating depression.

Depression is a prevalent mood disorder that affects millions of people worldwide, leading to feelings of sadness, hopelessness, and loss of interest in daily activities. In this article, we will explore these two medications in detail, comparing their mechanisms of action, effectiveness, side effects, and considerations for choosing one over the other.

Understanding Depression and Antidepressants

Depression and anxiety are two of the most common mental health disorders affecting millions of people worldwide. The impact of these conditions on an individual's well-being and daily functioning can be profound, leading to a diminished quality of life. In response to the growing prevalence of these disorders, the field of medicine has developed a range of medications aimed at alleviating symptoms and providing relief. Understanding Depression and Anxiety Medications is a crucial step in empowering patients, caregivers, and healthcare professionals to make informed decisions about treatment options.

This introduction sets the stage for exploring the world of antidepressants and anti-anxiety drugs, their mechanisms of action, potential benefits, and considerations when incorporating them into a comprehensive mental health treatment plan. By shedding light on these medications' complexities and benefits, we aim to foster a greater understanding of how they can play a pivotal role in restoring hope and serenity to those grappling with depression and anxiety.

Introducing Viibryd

Viibryd, also known by its generic name vilazodone, belongs to the class of selective serotonin reuptake inhibitors (SSRIs) and is unique because it combines SSRIs with partial serotonin receptor agonism. This dual mechanism of action helps in increasing serotonin levels and activating certain serotonin receptors to improve mood.

How Viibryd Works

Viibryd works primarily by inhibiting the reuptake of serotonin in the brain, which leads to increased levels of serotonin available to bind to receptors. Additionally, it acts as a partial agonist at the serotonin 5-HT1A receptor, which further enhances its antidepressant effects. This combination allows Viibryd to target both serotonin reuptake and receptor activity, resulting in a more comprehensive approach to managing depression.

Effectiveness and Safety

Clinical trials have demonstrated the efficacy of Viibryd in alleviating symptoms of depression. Many individuals have reported significant improvements in their mood and overall well-being while taking this medication. However, as with all antidepressants, Viibryd may not be suitable for everyone, and its safety and effectiveness should be assessed on an individual basis.

Introducing Trintellix

Trintellix, with the generic name vortioxetine, is a different type of antidepressant known as a serotonin modulator and stimulator. It acts on various serotonin receptors and also provides cognitive benefits by improving cognitive function and cognitive flexibility.

How Trintellix Works

Trintellix works by increasing serotonin levels in the brain and interacting with several serotonin receptors. It acts as a serotonin reuptake inhibitor, similar to SSRIs, while also affecting other receptors such as 5-HT1A, 5-HT1B, 5-HT3, and 5-HT7. This unique mechanism allows Trintellix to offer not only antidepressant effects but also potential cognitive improvements.

Effectiveness and Safety

Trintellix has demonstrated efficacy in treating depression, with clinical studies showing positive outcomes in individuals with major depressive disorder. It is generally well-tolerated, but individual responses to the medication may vary. It is crucial to work with a healthcare provider to monitor treatment progress and make any necessary adjustments.

Viibryd vs Trintellix : Safety Profiles

Safety is a paramount concern when considering antidepressant medications. In this section, we will delve deeper into the potential side effects and risks associated with both Viibryd and Trintellix.

Common Side Effects:

Both Viibryd and Trintellix may lead to common side effects, including gastrointestinal disturbances, headaches, and changes in sexual function. We will provide detailed information about these side effects, their prevalence, and how they may vary between the two medications.

Less Common or Serious Side Effects:

While most side effects are mild and manageable, some individuals may experience less common or more severe reactions. We will discuss these rarer side effects and the importance of promptly informing healthcare providers if any adverse reactions occur.

Potential Risks and Precautions:

Certain individuals may be at higher risk of experiencing specific side effects due to their medical history or concomitant medications. We will outline potential risks and precautions associated with Viibryd and Trintellix, emphasizing the significance of open communication with healthcare providers.

Comparing Viibryd and Trintellix

Mechanism of Action

The primary difference between Viibryd and Trintellix lies in their mechanisms of action. While both medications increase serotonin levels in the brain, Viibryd combines SSRIs with partial agonism at serotonin receptors, while Trintellix targets multiple serotonin receptors and offers cognitive benefits.

Efficacy in Treating Depression

Both Viibryd and Trintellix have been found to be effective in treating depression, but individual responses to these medications can vary. What works well for one person may not be as effective for another. Therefore, it is crucial for individuals to work closely with their healthcare providers to find the most suitable treatment option for their specific needs.

Side-by-Side Comparison

Aspect	Viibryd	Trintellix
Mechanism of Action	SSRIs + Serotonin 5-HT1A Agonist	Serotonin Modulator + Various Receptor Interactions
Cognitive Benefits	No	Yes
Common Side Effects	Nausea, Diarrhea, Headache, Sexual Dysfunction	Nausea, Constipation, Sexual Dysfunction

Choosing Between Viibryd and Trintellix

When choosing between Viibryd and Trintellix, several factors need to be considered, including the individual's medical history, previous treatment responses, lifestyle, and preferences. It is essential to have an open and honest discussion with a healthcare provider to determine which medication aligns best with the individual's specific needs.

Lifestyle and Behavioral Strategies for Managing Depression

In addition to medication, lifestyle changes and behavioral strategies can significantly contribute to managing depression. Regular physical activity, a balanced diet, and seeking support through therapy or counseling can enhance the overall well-being of individuals dealing with depression.

Understanding Perplexity and Burstiness in Depression Treatment

Depression treatment can be perplexing due to the varying responses individuals may have to different medications. Additionally, burstiness in treatment occurs when sudden changes in mood or symptoms are experienced. Personalized treatment plans that account for these complexities are essential to achieving successful outcomes.

Viibryd vs Trintellix: Potential Drug Interactions and Precautions

As with any medication, both Viibryd and Trintellix can interact with other drugs, supplements, or substances, potentially affecting their efficacy or leading to adverse effects. It is essential for patients and healthcare providers to be aware of these potential drug interactions and take necessary precautions to ensure safe and effective treatment.

Viibryd vs Trintellix: Drug Interactions

a. Monoamine Oxidase Inhibitors (MAOIs): Combining Viibryd or Trintellix with MAOIs can lead to a severe and potentially life-threatening condition called serotonin syndrome. Therefore, a minimum 14-day washout period is necessary between stopping MAOIs and starting either of these medications.

b. Serotonergic Drugs: Both Viibryd and Trintellix increase serotonin levels in the brain. Combining them with other serotonergic medications, such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), can elevate serotonin to dangerous levels and cause serotonin syndrome.

c. Warfarin and Anticoagulants: Viibryd and Trintellix may interact with blood-thinning medications like warfarin, increasing the risk of bleeding. Close monitoring of blood clotting times is essential when using these medications together.

d. CYP450 Enzyme Inhibitors: Viibryd is metabolized by the CYP3A4 enzyme, and Trintellix is metabolized by the CYP2D6 enzyme. Drugs that inhibit these enzymes may lead to higher levels of Viibryd or Trintellix in the body, increasing the risk of side effects.

Viibryd vs Trintellix: Precautions

a. Allergic Reactions: Individuals with a history of hypersensitivity to Viibryd, Trintellix, or any of their components should avoid using these medications.

b. Pregnancy and Breastfeeding: The safety of Viibryd and Trintellix during pregnancy and breastfeeding has not been fully established. Consultation with a healthcare provider is crucial for pregnant or breastfeeding individuals.

c. Hepatic Impairment: Caution is advised when administering Viibryd or Trintellix to patients with liver problems, as these drugs undergo hepatic metabolism.

d. Renal Impairment: In cases of severe kidney impairment, dosage adjustments may be necessary, as the elimination of Viibryd and Trintellix can be affected.

e. Bipolar Disorder and Mania: Both medications may precipitate manic episodes in patients with bipolar disorder. Close monitoring is essential for those with a history of bipolar disorder or mania.

f. Suicidal Thoughts: Antidepressant medications, including Viibryd and Trintellix, have been associated with an increased risk of suicidal thoughts, especially in young adults. Patients should be closely monitored for any changes in mood or behavior.

g. Discontinuation: Abruptly stopping Viibryd or Trintellix may lead to withdrawal symptoms. Tapering the dosage under medical supervision is recommended when discontinuing these medications.

It is crucial for patients to provide a comprehensive list of all medications, supplements, and substances they are using to their healthcare providers before starting Viibryd or Trintellix.

Viibryd vs Trintellix: Cost Comparison

Generally, the cost of brand-name medications like Trintellix tends to be higher compared to generic alternatives like Viibryd. A 30 tablet pack of Trintellix will most likely cost above $400 while for Viibryd it will be around $50. Generic versions of Viibryd (vilazodone) are likely to be more cost-effective. However, it's essential to check with local pharmacies or online retailers for accurate and up-to-date pricing information.

To get the most accurate and current cost comparison of Viibryd and Trintellix, I recommend reaching out to local pharmacies or consulting with a healthcare provider. Additionally, you may consider using prescription drug price comparison websites or apps to find the best prices available in your area. Always remember to check if your health insurance covers any part of the medication's cost, as it can significantly impact the out-of-pocket expenses.

Viibryd vs Trintellix: Final Verdict

Viibryd and Trintellix are both valuable options in the treatment of depression, offering unique mechanisms of action and potential benefits. Choosing the right antidepressant requires careful consideration of individual factors and close collaboration with a healthcare provider. Remember that the journey to finding the most suitable medication may involve some trial and error, and it is essential to remain patient throughout the process.

As depression can have a significant impact on one's life, seeking professional help and adhering to prescribed treatment plans are vital steps in managing this condition effectively. In addition to medication, seeking therapeutic help can also be beneficial in treating depression. With the right treatment, support, and lifestyle adjustments, individuals can regain control of their lives and work towards improved mental well-being.

FAQs

What is the closest drug to Trintellix?

The closest drug to Trintellix is probably Lexapro (Escitalopram). Both Trintellix and Lexapro are antidepressant medications that work on serotonin levels in the brain, although they have different mechanisms of action and potential side effects.

What antidepressant is comparable to Trintellix?

One antidepressant comparable to Trintellix is Zoloft (Sertraline). Both Trintellix and Zoloft are commonly prescribed for the treatment of depression and may have overlapping effectiveness and side effect profiles.

Why Trintellix is the best?

The term "best" is subjective and varies from person to person. Trintellix may be considered a favorable option for some individuals due to its unique mechanism of action and potential cognitive benefits. However, the choice of the "best" antidepressant depends on individual factors, medical history, and response to treatment.

What drug is similar to Viibryd?

One drug similar to Viibryd is Celexa (Citalopram). Both Viibryd and Celexa are antidepressants in the SSRI class, although they have different pharmacological profiles and potential side effects.

What is a less expensive alternative to Trintellix?

A less expensive alternative to Trintellix could be generic versions of other antidepressants, such as generic Sertraline or generic Fluoxetine. These medications are often more cost-effective while providing similar therapeutic effects.

Is Trintellix better for depression or anxiety?

Trintellix is primarily prescribed for the treatment of depression. While some antidepressants may also help with anxiety symptoms, Trintellix's main indication is for depressive disorders. Patients with comorbid depression and anxiety should consult their healthcare provider to determine the most suitable treatment.

What is a natural alternative to Trintellix?

There are no natural alternatives that directly mimic the action of Trintellix. However, some individuals find relief from depression symptoms through lifestyle changes, exercise, mindfulness practices, and counseling. It is essential to consult a healthcare provider before solely relying on natural approaches for treating depression.

Is Trintellix a mood stabilizer?

No, Trintellix is not classified as a mood stabilizer. It belongs to the class of antidepressant medications known as serotonin modulators and stimulators, targeting serotonin receptors in the brain to alleviate depression symptoms.

What medications are in the same class as Trintellix?

Trintellix belongs to the serotonin modulator and stimulator class of antidepressants. Other medications in this class include vortioxetine (the generic name for Trintellix), Luvox (Fluvoxamine), and Viibryd (Vilazodone).

Is Trintellix energizing?

Trintellix's effect on energy levels can vary among individuals. While some people may experience increased energy and motivation, others may not notice significant changes in energy levels. Trintellix's impact on energy should be discussed with a healthcare provider to determine its suitability.

What do people say about Trintellix?

People's experiences with Trintellix can vary widely. Some individuals may find it effective in managing depression with minimal side effects, while others may have different responses. It is essential to consider individual experiences and consult with a healthcare provider for personalized guidance.

Is Trintellix calming?

Trintellix's effects on mood can include feelings of calmness and improved well-being for some individuals. However, like any medication, individual responses may differ, and some people may not experience a calming effect. Regular communication with a healthcare provider is essential to monitor treatment progress.

What is the strongest antidepressant medication?

There is no single "strongest" antidepressant, as the effectiveness of these medications depends on the individual's unique biology and response to treatment. Different antidepressants may be more suitable for different people based on their specific needs and medical history.

Do you gain weight on Viibryd?

Weight gain is not commonly associated with Viibryd use. However, individual responses to antidepressants can vary, and weight changes may occur due to factors such as improved appetite or other medication interactions. It is essential to discuss any concerns about weight with a healthcare provider.

Does Viibryd help anxiety?

Viibryd is primarily indicated for the treatment of major depressive disorder, but it may also have some positive effects on anxiety symptoms for certain individuals. However, the use of Viibryd specifically for anxiety disorders would require careful evaluation and guidance from a healthcare provider.

References

National Institute of Mental Health (NIMH) - www.nimh.nih.gov
U.S. Food and Drug Administration (FDA) - www.fda.gov
American Psychiatric Association (APA) - www.psychiatry.org

July 24, 2023 0 comment

Trintellix vs Lexapro: Antidepressant Showdown for the Mind

by Dr Mahmood Rehan July 22, 2023

written by Dr Mahmood Rehan

Let’s look into the phenomenon of Trintellix vs Lexapro. To put it briefly, Trintellix is a multimodal antidepressant targeting multiple serotonin receptors, while Lexapro is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin availability in the brain.

In this article, we will delve into the detailed comparison between two popular antidepressants - Trintellix and Lexapro. Both drugs are widely prescribed for the treatment of depression, but they have distinct characteristics that may make one more suitable than the other for certain individuals. By understanding their differences and similarities, you can work with your healthcare provider to find the most suitable option for your specific needs.

Introduction to Antidepressants

Antidepressants play a crucial role in the field of mental health, offering hope and relief to millions of individuals worldwide. These medications belong to a class of drugs designed to treat various mood disorders, with depression being the most common. The primary goal of antidepressants is to restore the balance of neurotransmitters, such as serotonin, norepinephrine, and dopamine, in the brain. These chemicals are essential for regulating mood, emotions, and overall mental well-being.

Antidepressants come in different types, including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), and others. Each type targets specific neurotransmitters, leading to varied effects and potential side effects. When prescribed and used correctly under the guidance of a healthcare professional, antidepressants can significantly improve the quality of life for those struggling with mood disorders, providing them with a pathway towards emotional stability and a more positive outlook on life.

Understanding Trintellix: Mechanism and Benefits

Trintellix, also known by its generic name vortioxetine, is a widely prescribed antidepressant that has gained recognition for its unique mechanism of action. This article delves into the science behind Trintellix and how it works in the brain to alleviate symptoms of depression. By targeting multiple serotonin receptors, Trintellix helps regulate serotonin levels, which plays a crucial role in mood regulation. Additionally, we explore the potential benefits of Trintellix beyond traditional antidepressants, such as its impact on cognitive symptoms associated with depression. Understanding Trintellix's mechanism and benefits can help individuals make informed decisions when considering this medication as part of their treatment plan.

Unraveling Lexapro: How It Works and Its Advantages

Lexapro, or escitalopram, is another popular antidepressant widely prescribed to manage depression and anxiety disorders among others. In this section, we unravel the science behind Lexapro's mode of action in the brain. By inhibiting serotonin reuptake, Lexapro increases the availability of serotonin, promoting mood stabilization and alleviating symptoms of depression. Furthermore, we explore the specific advantages of Lexapro, including its efficacy in addressing anxiety-related symptoms. Unraveling Lexapro's mechanisms and advantages provides valuable insights for those seeking an effective antidepressant option to improve their mental well-being.

Trintellix vs Lexapro: Chemical Composition

Trintellix (Vortioxetine)

Trintellix, known by its generic name vortioxetine, is an antidepressant belonging to a class of drugs called serotonin modulators and stimulators (SMS). Its chemical structure consists of a bicyclic compound with a molecular formula of C18H22N2S. Vortioxetine is a selective serotonin reuptake inhibitor (SSRI) with an additional mechanism of action involving serotonin receptor activity. This unique multimodal approach sets Trintellix apart from other traditional SSRIs.

Lexapro (Escitalopram)

Lexapro, or its generic name escitalopram, falls under the category of selective serotonin reuptake inhibitors (SSRIs). Its chemical structure is based on the S-enantiomer of citalopram, and its molecular formula is C20H21FN2O. As an SSRI, Lexapro functions by inhibiting the reuptake of serotonin in the brain, leading to increased serotonin levels, which play a vital role in mood regulation.

Both Trintellix and Lexapro target serotonin levels in the brain to alleviate symptoms of depression, but their chemical compositions and mechanisms of action set them apart, resulting in different effects and potential benefits for individuals with depression. It is crucial to consult a healthcare provider to determine the most appropriate medication based on an individual's specific needs and medical history.

The Battle of the Serotonin Reuptake Inhibitors

The battle between Trintellix and Lexapro takes center stage in this article as we compare the two popular serotonin reuptake inhibitors (SSRIs). Both medications have proven efficacy in treating depression, but they differ in their mechanisms and specific effects. Through a comprehensive analysis, we shed light on the distinctions between Trintellix and Lexapro, helping readers better understand which aspects of depression each drug targets. By exploring this comparative review, individuals can gain a clearer perspective on choosing the most suitable medication for their unique needs.

Efficacy and Safety: Trintellix vs Lexapro

Effectiveness and safety are vital considerations when choosing an antidepressant. This segment thoroughly assesses the efficacy and safety profiles of both Trintellix and Lexapro. Clinical studies, side effect profiles, and potential risks associated with each medication are discussed in detail. By understanding the efficacy and safety of these drugs, individuals can engage in informed discussions with their healthcare providers to determine the most appropriate treatment option.

Trintellix vs Lexapro: Side Effects and Risks

Trintellix (Vortioxetine)

Trintellix, like all medications, may cause side effects in some individuals. Common side effects of Trintellix include nausea, vomiting, diarrhea, and constipation. These gastrointestinal symptoms usually occur within the first few weeks of treatment and may improve over time. Other common side effects include dizziness, dry mouth, and sexual dysfunction.

Less common side effects of Trintellix may include headaches, fatigue, increased sweating, and changes in appetite or weight. Some individuals may experience sleep disturbances, such as insomnia or vivid dreams. Additionally, Trintellix can cause serotonin syndrome, a potentially serious condition that may occur when there is an excess of serotonin in the body. Symptoms of serotonin syndrome may include confusion, hallucinations, rapid heart rate, fever, and muscle stiffness.

It is essential to report any unusual or severe side effects to a healthcare provider promptly. In rare cases, Trintellix may also cause allergic reactions, with symptoms like rash, itching, swelling, severe dizziness, and difficulty breathing. If any of these symptoms occur, seek immediate medical attention.

Lexapro (Escitalopram)

Similar to Trintellix, Lexapro may cause side effects in some individuals. Common side effects of Lexapro include nausea, dry mouth, dizziness, and drowsiness. These side effects are usually mild and temporary, often improving as the body adjusts to the medication.

Lexapro may also lead to changes in sleep patterns, such as insomnia or increased sleepiness. Some individuals may experience sexual dysfunction, including reduced libido and difficulty achieving orgasm.

Less common side effects of Lexapro may include sweating, tremors, headache, and gastrointestinal symptoms like diarrhea or constipation. In rare cases, Lexapro may cause serotonin syndrome, especially when taken with other medications that increase serotonin levels.

Lexapro may also affect mood in some individuals, leading to increased anxiety or agitation. If any significant changes in mood occur, it is essential to notify a healthcare provider promptly.

Trintellix vs Lexapro: Cost Comparison

When considering the cost of antidepressants, generic versions are often more affordable than brand-name medications. In the case of Lexapro, its generic form, escitalopram, has been available for some time, offering a cost-effective option for patients and healthcare systems. Due to its popularity and availability in generic form, Lexapro is the more budget-friendly choice for individuals and insurance plans as it costs around $50 for a 30 tablet pack.

Trintellix, being a newer medication, more expensive than Lexapro and may not yet have a generic version available, further contributing to its higher cost. It costs around $500 for a 30 tablet pack. For patients without insurance coverage or with high co-pays, the cost difference between Trintellix and Lexapro might be a significant consideration when deciding on a suitable antidepressant.

However, it's essential to note that the cost comparison should not be the sole determining factor when choosing an antidepressant. The effectiveness, tolerability, and potential benefits for an individual's specific condition should take precedence, and healthcare providers consider these factors during the decision-making process.

Trintellix vs Lexapro: Which One is Better Suited for You?

Deciding which antidepressant is better suited for an individual is a personalized process that involves careful assessment. Trintellix and Lexapro both offer effective treatment for depression, but the choice depends on the specific symptoms, medical history, and individual response to the medications. Trintellix's unique multimodal mechanism of action might be more suitable for those experiencing cognitive symptoms of depression, while Lexapro's effectiveness in managing anxiety-related symptoms can be advantageous for others. It is crucial to consult with a qualified healthcare provider to discuss your specific needs and preferences, enabling them to recommend the most appropriate antidepressant tailored to your well-being and overall mental health.

Combining Antidepressants with Therapy: What Works Best?

In many cases, combining antidepressant medication with therapy can enhance treatment outcomes. In this section, we explore the benefits of integrating therapy alongside Trintellix or Lexapro. We discuss the various therapeutic approaches, such as cognitive-behavioral therapy (CBT) and mindfulness-based techniques, and how they can complement the effects of medication. Understanding the potential synergies between antidepressants and therapy empowers individuals to take a holistic approach to managing their mental health.

Exploring Alternative Treatments for Depression

Alternative treatments for depression refer to therapeutic approaches and interventions that are outside the realm of conventional medication and psychotherapy. While antidepressant medications and talk therapy (such as cognitive-behavioral therapy) are the primary treatments for depression, alternative treatments offer additional options that may complement traditional approaches or be utilized as standalone methods for managing depression. These alternative treatments aim to address the emotional, psychological, and physical aspects of depression and can be particularly appealing to individuals seeking holistic and natural approaches to improve their mental well-being.

Here are some common alternative treatments for depression:

Mindfulness and Meditation: Mindfulness practices, such as meditation and deep-breathing exercises, focus on cultivating present-moment awareness and reducing stress. Mindfulness techniques have shown promise in reducing depressive symptoms, promoting emotional regulation, and enhancing overall well-being.
Yoga and Exercise: Engaging in regular physical activity, including yoga, has been found to have mood-enhancing effects. Exercise releases endorphins, the body's natural feel-good chemicals, which can help reduce feelings of sadness and anxiety.
Herbal Supplements: Certain herbal supplements, such as St. John's Wort and Saffron, have been studied for their potential antidepressant effects. However, it's essential to exercise caution and consult a healthcare provider before using any herbal supplement, as they may interact with other medications or have side effects.
Acupuncture: Acupuncture, an ancient Chinese practice that involves inserting thin needles into specific points on the body, is believed to rebalance energy flow. Some studies suggest that acupuncture may help reduce depressive symptoms and improve overall mood.
Nutrition and Diet: Adopting a balanced and nutritious diet can positively impact mood and energy levels. Certain nutrients, such as omega-3 fatty acids and B vitamins, have been associated with better mental health.
Social Support and Therapy Groups: Connecting with others who have similar experiences through support groups or group therapy can provide a sense of belonging and understanding, reducing feelings of isolation and depression.
Art and Music Therapy: Engaging in creative activities, such as art or music therapy, can be a therapeutic outlet for expressing emotions and processing difficult feelings associated with depression.
Aromatherapy: The use of essential oils in aromatherapy has been suggested to have calming and uplifting effects, potentially reducing stress and anxiety.

It is crucial to note that while alternative treatments can be beneficial for some individuals, they are not a substitute for professional medical advice or conventional treatments.

Tapering off Antidepressants: A Guide to Discontinuation

When it comes to discontinuing antidepressant medication, a carefully managed tapering process is crucial to minimize withdrawal effects and ensure a smooth transition. In this section, we provide a comprehensive guide on how to taper off Trintellix or Lexapro under the supervision of a healthcare professional. Understanding the tapering process and potential challenges empowers individuals to approach discontinuation with confidence and safety.

Trintellix vs Lexapro: FAQs

Is Trintellix better than Lexapro?

The efficacy of Trintellix and Lexapro may vary depending on individual responses and specific symptoms. Trintellix's unique multimodal mechanism of action makes it more suitable for individuals with cognitive symptoms, while Lexapro might be preferred for those experiencing anxiety-related aspects of depression. The choice between the two should be based on a thorough evaluation by a healthcare provider.

Is Trintellix better for depression or anxiety?

Trintellix is primarily prescribed for depression, and its mechanism of action targets cognitive symptoms. While it may have some benefits for anxiety, Lexapro is generally considered a more effective option for managing anxiety-related symptoms.

Why is Trintellix better than other antidepressants?

Trintellix's advantage lies in its multimodal mechanism, which sets it apart from traditional SSRIs. It targets multiple serotonin receptors, potentially addressing cognitive symptoms that other antidepressants may not alleviate as effectively.

Is there a better antidepressant than Lexapro?

The effectiveness of antidepressants can vary among individuals. Some people may respond better to Lexapro, while others may find relief with different medications. It is essential to work with a healthcare provider to find the most suitable antidepressant based on individual needs.

Does Trintellix cause weight gain?

Weight changes, including both weight gain and weight loss, have been reported with Trintellix usage, but the incidence is relatively low. If weight changes occur, it's important to discuss them with a healthcare provider to explore appropriate management strategies.

What is the closest drug to Trintellix?

There is no exact equivalent to Trintellix, given its unique multimodal mechanism. However, other SSRIs and newer antidepressants may share some similarities in their effects and indications.

Why is Trintellix so good?

Trintellix's effectiveness lies in its unique ability to target various serotonin receptors, potentially providing benefits for cognitive symptoms of depression. However, individual responses may vary, and what works well for one person may not be as effective for another.

Does Trintellix make you feel good?

Trintellix aims to alleviate symptoms of depression, improving overall mood and well-being. However, individual experiences with the medication may differ, and it is essential to work closely with a healthcare provider to monitor its effects.

What is the number one antidepressant for anxiety?

The number one antidepressant for anxiety may vary based on individual responses and medical history. SSRIs like Lexapro and SNRIs (serotonin-norepinephrine reuptake inhibitors) are commonly prescribed for anxiety management.

Does Trintellix make you have energy?

Trintellix may have varying effects on energy levels among individuals. Some users may experience increased energy, while others may not notice significant changes. It is crucial to discuss any concerns with a healthcare provider.

Does Trintellix help with energy and motivation?

Trintellix may provide improvements in energy and motivation for some individuals, as these can be connected to the overall improvement in mood and well-being that the medication aims to achieve.

Why switch to Trintellix?

Switching to Trintellix may be considered if an individual does not respond well to other antidepressants or experiences specific cognitive symptoms that could benefit from its unique multimodal mechanism.

What is a good replacement for Lexapro?

When considering a replacement for Lexapro, other SSRIs or SNRIs may be suitable alternatives. However, the choice should be made in consultation with a healthcare provider based on individual needs.

What is the downside of Lexapro?

Some individuals may experience side effects with Lexapro, such as nausea, headache, or changes in sleep patterns. However, these side effects are generally mild and transient in nature.

What is the closest drug to Lexapro?

The closest drug to Lexapro is its generic form, escitalopram. It has the same active ingredient and is prescribed for similar indications as Lexapro.

References

National Institute of Mental Health (NIMH) - https://www.nimh.nih.gov/
Centers for Disease Control and Prevention (CDC) - https://www.cdc.gov/
World Health Organization (WHO) - https://www.who.int/
American Psychiatric Association (APA) - https://www.psychiatry.org/

July 22, 2023 0 comment

Depression Symptoms

Interactions and Side Effects of Using Wellbutrin and Alcohol Together

by Healthlinear February 2, 2021

written by Healthlinear

Wellbutrin and alcohol, when consumed together, put the patient at high risk for serious health impairments, nausea, vomiting, and seizures. We know that antidepressant medication is an important tool for people who struggle with depression and anxiety on a daily basis. As is the case with all drugs, most antidepressants can have certain dangerous side effects if consumed with alcohol. Wellbutrin is one such antidepressant that interacts dangerously with alcohol.

What is Wellbutrin?

Wellbutrin is the brand name of the generic drug Bupropion. It is a prescription drug used to treat different types of clinical depression. Wellbutrin is a norepinephrine-dopamine reuptake inhibitor (NDRI). It is usually prescribed to people who don’t respond well to other antidepressant medication. It is available in different tablet forms, including extended-release (XL), sustained-release (SR), and immediate-release (IR) variations.

Wellbutrin is an FDA (Food and Drug Administration) approved treatment for major depressive disorder (MDD) and seasonal affective disorder (SAD), also known as “winter depression”. Wellbutrin is distinctive from other antidepressants because it doesn’t affect your weight, libido and sexual desires as some other antidepressants are wont to do. Because of this quality, Wellbutrin is often prescribed in combination with other antidepressants to help counteract the side-effects that affect sexual desire.

Off-Label Uses for Wellbutrin:

While the FDA approved use for Wellbutrin is to treat MDD and SAD, wellbutrin is frequently prescribed off-label to alleviate the symptoms of attention-deficit/hyperactivity disorder (ADHD), anxiety, bipolar disorder, and obesity. It can also be used to help people quit smoking. Furthermore it can help with PTSD, social anxiety disorder, and nerve pain.

Interactions of Wellbutrin with other medication:

As with other drugs, there are potential interactions that may occur when Wellbutrin is taken at the same time as other substances. Some medications that increase the risks of side effects include:

Antipsychotics
Blood thinners
Corticosteroids
Thyroid medications
Monoamine oxidase inhibitors
OTC pain relievers such as ibuprofen
Amphetamine and dextroamphetamine
Diabetes medications including metformin
Other antidepressants including Prozac, Zoloft, and Effexor

Interaction of Wellbutrin with Alcohol:

Wellbutrin and alcohol have a complicated relationship. Even though some people can drink occasionally without side-effects while on Wellbutrin, abusing alcohol regularly while you are on Wellbutrin can have seriously adverse effects on your health. If you are not a frequent or regular drinker, drinking alcohol while you are on Wellbutrin can induce side effects like seizures and having suicidal thoughts. On the other hand, heavy drinkers may also experience seizures if they abruptly stop imbibing while on Wellbutrin.

Some known risks of mixing Wellbutrin and alcohol:

Nausea
Fatigue
Seizures
Paranoia
Vomiting
Blackouts
Dizzy spells
Blurred vision
Poor judgment
Suicidal thoughts
Alcohol poisoning

Long-Term Effects Of Mixing Alcohol And Wellbutrin

Alcohol should be used cautiously, but even more so for people battling depression. Alcohol is a natural depressant. Mixing alcohol with Wellbutrin increases the side effects of both Alcohol and Wellbutrin, and it also increases the likelihood of developing an unhealthy dependence or addiction to alcohol.

Combining Wellbutrin and alcohol regularly can have long-term effects including:

Increased overdose risk
Increased risk of alcohol addiction
Decreased Wellbutrin effectiveness

If you take Wellbutrin and want to know how it will interact with alcohol, consult your doctor and discuss your alcohol habits truthfully. Wellbutrin is not the only antidepressant that is not supposed to be taken with alcohol. It is highly inadvisable to consume Lexapro and Alcohol together. You should consult your doctor before making any changes in your drinking routine.

FAQs:

Is it safe to drink alcohol while taking Wellbutrin?
Short answer, No. Long answer, still no. It can cause suicidal thoughts and tendencies and cause more depression.

Can Wellbutrin cause personality changes?
Wellbutrin may cause some people to become nervous, ill-tempered, agitated, and display other abnormal behavior.

How much weight can you lose on Wellbutrin?
Weight loss is a purported side effect of Wellbutrin but the reasons may not be directly related to the drug. Studying the correlation of Wellbutrin and weight change Both weight loss and weight gain have been observed.

Does Wellbutrin increase your sex drive?
Wellbutrin has a positive impact on libido, but it does not cause hypersexuality.

Does Wellbutrin help you focus?
Wellbutrin is a norepinephrine and dopamine reuptake inhibitor (NDRI). It operates by keeping the neurotransmitters norepinephrine and dopamine available to your brain's neurons for longer. This helps improve concentration, focus, and other ADHD symptoms.

Will Wellbutrin help me sleep?
The antidepressant Wellbutrin (bupropion) is linked to insomnia. However, studies examining the electrical activity in the brain of patients taking bupropion indicate that the drug actually increases REM sleep time.

References:

Fava, Maurizio et al. “15 years of clinical experience with bupropion HCl: from bupropion to bupropion SR to bupropion XL.” Primary care companion to the Journal of clinical psychiatry vol. 7,3 (2005): 106-13. doi:10.4088/pcc.v07n0305
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1163271/

Grover, Sandeep, and Partha Pratim Das. “Can bupropion unmask psychosis.” Indian journal of psychiatry vol. 51,1 (2009): 53-4. doi:10.4103/0019-5545.44907
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2738405/

Karam-Hage, Maher et al. “Bupropion-SR for smoking reduction and cessation in alcohol-dependent outpatients: a naturalistic, open-label study.” Current clinical pharmacology vol. 9,2 (2014): 123-9. doi:10.2174/1574884708666131112124429
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056335/

Schramm, Preetam J et al. “Bupropion response on sleep quality in patients with depression: implications for increased cardiovascular disease risk.” European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology vol. 24,2 (2014): 207-14. doi:10.1016/j.euroneuro.2013.09.007
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948318/

Hill, Stanley et al. “A case report of seizure induced by bupropion nasal insufflation.” Primary care companion to the Journal of clinical psychiatry vol. 9,1 (2007): 67-9. doi:10.4088/pcc.v09n0114a
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894833/

February 2, 2021 0 comment

Depression Health

Daith Piercing for Anxiety

by Healthlinear October 2, 2020

written by Healthlinear

Daith piercing for anxiety is getting more popular as time passes as more people are knowing about this. People are slowly acknowledging it. However some still don’t know what it is. Daith piercing is the piercing in the inner cartilage fold of the ear and is below the rook piercing. It is believed that the daith piercing is done to ease the anxiety. It also helps to relieve other such symptoms like headaches and anxiety. According to some people there are some of the points where when pressure applied. This can help release the anxiety a little bit. There is no understanding of exactly how the daith piercing helps with the anxiety and migraine issues. But there are a few proposed mechanisms that can help us understand how the daith piercing works.

How the Daith piercing works

The ear is considered to have a few pressure points. These pressure points are how the holistic health practitioners like the acupuncturists work to relieve some of the symptoms. It helps with the treatment of a few problems. This type of mechanism of the action revolves around putting pressure on the vagus nerve. There are ten nerves extensions from the base of the brain. However the vagus nerve happens to be the largest among all. Pressure on this specific nerve has proven to help with a lot of conditions like epilepsy and depression. So, putting pressure will help the stimulation of the vagus nerve. Constant pressure on such a nerve can help you get rid of some of these health problems like the migraine and the anxiety. Even more, researches are being done to check if this can help with the other health conditions as well.

Researches about the Daith piercing

There have not ever been any clinical researches done on the clinical benefits of the Daith piercing. But there has been a lot of studies and even more, are done to understand the clinical importance and other health benefits of the Daith piercing. The studies indicate that acupuncture is a very promising treatment for panic attacks and anxiety. As you might know, the acupuncturist puts the pressure in certain pressure points in your body to alleviate the symptoms. This particular point is where the acupuncturist it’s the pressure. So having a piercing there will put a constant pressure and will help relieve the migraine.

Considering it is a placebo effect

The placebo effect is the effect where the pills that are given have no medicinal property but patient does not know that. That can heal patients who consider themselves ill psychologically only and have no real problem with them systemically. That is why some people think that daith piercing can be that. For the people who know that this type of piercing is to alleviate anxiety and migraine can be responding to this method. This is the reason why it is considered a placebo effect by some.

One expert at the Cleveland clinic has claimed that the daith piercing helps because it is a placebo effect when it comes to migraines. Whereas, as far as anxiety is concerned, this effect helps only if the migraine is one of the symptoms of the anxiety in that patient. But since acupuncture works better than other placebo treatments in patients with migraines and anxiety so it can be proven to some extent that putting pressure at that particular point by piercing can be the reason why the patients recover from migraine and anxiety after the daith piercing.

Side of Daith piercing

Basically, when people are getting the daith piercing, there has been some confusion as to which side they should get this piercing. Basically, when you are getting the daith piercing to treat your migraine, it becomes obvious that you should be getting it in the side of your head that hurts the most and where you get migraines more often. For most people, it’s just one side, but for some people, they get it on both sides. These people should get piercing where they get migraines more often. As far as the anxiety is concerned, it doesn’t matter which side of your ear, you should get the daith piercing. You can get the piercing on either side if you are getting it for the anxiety alone.

Side effects of getting daith piercing

Daith piercing is more painful than the one you get on your earlobe since the cartilage is also pierced; it can be a little bit more painful and will also take longer to heal just like any other cartilage piercings. With ear lobe piercing, even if you let it close the mark when you stop wearing earrings, it will disappear after sometime. But with the cartilage piercings like the daith piercing, if you let it close after some time, it will leave a very visible mark on your ear.

Hence make up your mind for that before you get the daith piercing. Another important thing that you need to know is that the daith piercing, just like any other piercings is more likely to get infected. The reason behind this is that it is close to hair and they can get tugged in the process. So, if you are getting an infection, make sure you consult your doctor before the infection can get worse. If you are taking any antiplatelet and other heart drugs, then you should stop it before getting your piercing. Because then you bleeding won’t stop due to that medicine.

Other things you need to consider

If you like piercings on different parts of your body, you are good to go. But there are a few things that you need to prepare yourself before the piercing.

You should know how daith piercing looks. Make sure you are ready to go for that kind of look and think if it’s cool or not.
You should consult with your doctor about this cure.
Talk thoroughly with the piercing professional.
You should also know how much this piercing cost because this type of medical treatment is not covered by insurance.

This piercing can be done to both men and women.

October 2, 2020 0 comment

Allergies Depression Health

Zoloft Reviews – Uses of Zoloft and How is it Better Than Prozac

by Healthlinear March 8, 2020

written by Healthlinear

Zoloft and Prozac are the medicines used for the treatment of pf depression and manic disorder but it is the Prozac and Zoloft reviews that tell us which mediation is better for the use. There is this wide class of drugs used for the treatment of depression and each one is suitable for the patient based on any important factor like any other disease, age, etc.

Different types of therapies are given in the depression and that may include medication or not. Prozac ad Zoloft have widely used medications for the treatment of depression.

Health Linear Zoloft Reviews

Zoloft, as you know, is an anti-depressant and is used in the treatment of depression and many other mental disorders like eating disorders, post-traumatic stress disorder, panic attacks, and obsessive-compulsive disorder along with the depression. This medication has a lot of benefits and will provide you with a sense of calm, good appetite, sleep and a better mood. He active ingredients drug present within this medicine is the Sertraline.

Sertraline belongs to the class of drugs that are responsible for treating the depression and all the other indications mentioned above. These drugs act by inhibiting the serotonin reuptake and thus increasing the amount of serotonin.

Indications for the Use of Zoloft 25mg

Zoloft 25 mg and Zoloft 50 mg is the most commonly used drug for the treatment of depression but the following are some of the other reason s this mediation is used for.

It helps with the post-traumatic stress disorder
Obsessive-compulsive disorder is resolved with these medications as it decreases the stress and thus your compulsion to obsess over the few things.
Anxiety disorders of any kind can be treated with this and that includes social anxiety as well.
Your sleeping pattern will also get better with the use of this medicine and your appetite will improve as well.

Basically, when you are starting to use this medication it is important to get some advice from your doctor or pharmacist, they guide you beforehand but in case you are unable to understand anything you should ask them again.

The following are some of the important things that you should know regarding the use of this medication.

Since it is an oral tablet the use of this medication is through oral route. You will also need to know if you can take it with food or not. With Zoloft tablets, you can take them either with food or nit because there are no restrictions to that but when it comes to the capsules you should take them along with your meal.
The dosage depends on your medical history and overall medical condition. Also if you have been taking this medication for the premenstrual problems then the doctor will advise you to take the medication every day for two weeks prior to your periods. Just like that depending on your condition or the indication it is given for the dose is alternated a lot.
When you are taking medication it is important to take it regularly usually when people start to feel better they stop their mediation almost immediately and that may even worsen the situation. When you need to be stopped the medication the dose is decreased gradually instead of just stop in the medication immediately.
The same is the case when the dose is given at the start. The doe is increased gradually. So you can’t take the medicine without discussing do with your doctor so you can know when to increase that dose. A sudden intake of such medicines especially Zoloft 25 mg will cause the side effects of this drug.

Side Effects

Side effects are very common with all kinds of drugs. It is more common with all the anti-depressants. Following are some of the side effects that you will experience with the use of this medication

Dizziness, dry mouth and nausea are common side effects with this medicine. You will also have trouble sleeping. These side effects are not serious but if they persist or are very intense then you should consult with a doctor or a pharmacist.
If you are having the serious side effects like dizziness, fainting, blood in stools, less sexual ability, etc. then you should consult your doctor right away.
If you have had an allergic reaction to this drug of a similar class of drugs then you should tell your doctor beforehand because this can lead to some serious allergic reactions.

So these are all the side effects that you can observe with the use of this medication. The side effects also become severe when you are not following the proper dosage regime.

Precautions and Interactions as Compared to Prozac Reviews

Following are some of the precautions that you need to take along with the interactions that can cause serious side effects and the same is the result with Prozac reviews

Of you have an allergy to this medicine or any other medicine you should tell your doctor about that.
Telling your doctor about your medication history is also important because some of the drugs may interact and decrease or increase the effect or side effects of another drug.
MAO inhibitor is used most commonly by such patients but these drugs may interact with the Zoloft and can cause reactions. Usually, it is recommended that the patient stop taking this medication two weeks before you have to take Zoloft.
You should also tell your doctor about any medicine that oy are taking and is causing you to sleep more. This can produce an additive effect and can be very dangerous in some of the cases.
This medicine will also cause some of the false test results and if such attest result arrive you don’t have to be worried about it and instead show it to your doctor along with the mediation that you are using currently.
If you have missed a dose let it stay like that and don’t try taking double doses the next time. Just inform your pharmacist or your doctor and leave it be.

With Prozac reviews, you will know better which drug is better in between two.

March 8, 2020 0 comment

Depression Health

Is it Okay to Take Cymbalta and Alcohol Together?

by Healthlinear September 1, 2018

written by Healthlinear

Before we go in detail whether Cymbalta and alcohol should be taken together or not and if not then why we should know in detail what Cymbalta is and how it acts in our body and what exactly is it used for. First of all the drug known as Cymbalta is used in the treatment of depression. Depression is the first thing that it is used in treatment for because it is also used in the treatment of some of the other disorders that are related to the depression and all of them are the mental disorders.

Depression is increasing in our society day by day and thankfully the awareness song the people is also increasing but still, most of the people show neglection when it comes to their mental health which is not the way to live a healthy life. For a healthy life you need to have a healthy mind and how can you have a healthy mind when you are going through depression. Depression is eating up the people a lot and it is the most occurring mental disorder.

Depression can occur in the people of all age groups but still, it occurs the most in the teenagers as compared to the adults and it is most common to occur in women as compared to the men. The symptoms of the depression are as follows

Weight loss/gain

Lack of attention

Lack of interest in the daily activities

Irregular sleep

Self-depravity

Self-loathing

Anger or irritability

So these were some of the symptoms of the depression.

Cymbalta

To understand whether the Cymbalta and alcohol are the good combination or not we need to understand the function of Cymbalta in our body. The drug that is present in Cymbalta is duloxetine which is an anti-depressant. Duloxetine is basically a selective serotonin-norepinephrine reuptake inhibitor and it is a thiophene derivative. This drug substance helps in the inhibition of the reuptake of the serotonin, norepinephrine and to some extent the dopamine too.

It helps in the treatment of depression by maintaining the balance of serotonin in the brain that gets disrupted in the depressive disorder. It is not only used in the treatment of depression but some also central nervous system disorders too and following are some of the other disorders that are Cymbalta is used in the treatment for.

Major depressive disorder
Generalized anxiety disorder
Fibromyalgia
Neuropathic pain
Chronic musculoskeletal pain
Diabetic neuropathic pain

Cymbalta is a very potent medication and this is why it is recommended not to use Cymbalta and alcohol in combination. Cymbalta is also used in to relieve the chemotherapy-induced neuropathic pain but most commonly this medicine is used for the treatment of depression.

Cymbalta and alcohol

Now coming toward the main topic of discussion which is whether the Cymbalta and alcohol can be taken in the combination or not and the answer to that is no. The reasons why Cymbalta and alcohol cannot be taken together are a lot and following are some of the reasons for the justifications

Effects of alcohol on depression

The first reason for why we shouldn’t take Cymbalta and alcohol together is that effect of alcohol towards the central nervous system is depressive and to come out of depression we cannot go for the drugs that depress our central nervous system. The effect of alcohol to the brain is like this that at first it causes that excitation of CNS and then it starts to depress it and while Cymbalta is the anti-depressant it will act as an antagonist and this will result in the no effect of the drug Cymbalta.

By the use of alcohol, Cymbalta will fail to produce the required result and this lead to the failure in the treatment and it will also result in the increase in the depression itself. Moreover using the Cymbalta and alcohol together can lead to some other symptoms that are stated as below.

Panic attacks
Sleep problems
Irritability
Changes in mood
Suicidal thoughts

So this shows us that how detrimental it is on our health is the use of Cymbalta and alcohol. So you should avoid taking alcohol for how long you are using Cymbalta.

Liver damage

It is no secret that what effect alcohol has on the liver. The function of the liver is to metabolize i.e. Break the substances and it also plays the role in the metabolism of the most of the drugs in our bod. Alcohol is one of these drugs that is being metabolized by the liver and drinking too much or drinking for the longer period of times can cause excessive damage to the liver itself and that liver damage occurs because it gets accumulated with a lot of toxins.

Now Cymbalta is also one of those drugs that are metabolized by the liver and it also has the potential to cause damage to the liver. So if we take Cymbalta and alcohol together our liver is at a great danger because both of these drugs have the potential to cause the liver damage so if we want to avoid that we should stop taking alcohol while we are on the Cymbalta therapy. But if you are a great fan of beer and cannot live without it at all then you should ask your doctor about whether you can have the occasional drink or not you should also ask your doctor before taking the drink so you don’t have to bear any consequences.

Discuss it with doctor

If you want to have alcohol even when you are under the therapy of depression and is being treated by Cymbalta then you should talk it through with your doctor because then your doctor will decide if you should take them together or not based upon the amount of dose of drug you are taking and your past and the current medical history. If you have any past liver disease history or such history in the family then the doctor will recommend you not to take Cymbalta and alcohol together.

September 1, 2018 0 comment

Depression Health

Lexapro Vs Zoloft – A True Comparison

by Healthlinear January 30, 2018

written by Healthlinear

Before discussing Lexapro vs Zoloft, let’s talk about health. Health is a very important aspect of our life and without health, there is no fun in the life. There shouldn’t be any compromise with the health either physical or mental health. To stay healthy we should take part in the healthy activities and stay around the people that are good for the mental health.

But in the today’s world, every person suffering from the health problem wither physical or the mental. The ratio of mental illness is increasing day by day because our attitude towards a healthy life is so negligent and most of the people in the underdeveloped countries don’t even consider the mental health at all and that is why most of such medical problems stay unresolved throughput there life. So this is why there should be more awareness about the mental health so people who are undergoing such sicknesses can seek help.

There are a lot of mental health problems that are found in the society these days land the most common among all of them is the depression. Most of the people in our society due to the burdens of life are going through depression and this ratio is increasing day by day.

Depression

Depression is a mental disorder in which our central nervous system becomes depressed and this mental disorder is occurring in a lot of people and the reasons behind this disorder a lot and mostly the current state of our society where everyone is busy doing their own thing and no one have time for each other and in this mad race of being better most of the people are suffering from depression. The symptoms of depression can help us realize the problem in the very early stage but the problem is that most people pay no attention to these signs and symptoms and some of them even don’t know the signs and symptoms. Following are the symptoms of the depression.

Anger
Sleep changes
Loss of energy
Loss of interest
Concentration problem
Weight loss
Self-loathing etc.

So these were some of the symptoms that are found in the people that are suffering from the depression. Depression must be diagnosed because in most of the people depression leads to that stage where they start considering suicide and most of the people even opt for the suicide. The studies have shown that depression is more common among the teenagers as compared to the adults and gender-wise it is more common among the women as compared to the men.

Treatment of depression

A lot of drugs are suggested for the treatment of depression by now and Lexapro and Zoloft are among those drugs. Both of the drugs are used for the treatment of depression which is why we will further discuss the Lexapro vs Zoloft comparison to help you understand which one is best for you in the case of depression. Lexapro is an antidepressant that contains the drug escitalopram and Zoloft is the anti-depressant that contains the drug known as sertraline.

The Lexapro vs Zoloft comparison will help us understand the difference between these two drugs and will help us make the better decision. The escitalopram is a serotonin reuptake inhibitor and the sertraline is same too and the fact they both are the selective serotonin reuptake inhibitor they are considered the exact same but it’s not the way it is.

The SSRI drugs act in such a way that they inhibit the reuptake of serotonin thus increasing the amount of serotonin in the brain and serotonin is the chemical that lightens the mood of a person and this help with the treatment of depression. In depression, the level of serotonin gets unbalances and these two drugs help in the balancing of this chemical in the brain. These drugs are similar too but there are also some differences that support the Lexapro vs Zoloft argument.

Lexapro vs Zoloft

The first thing that we should know in the Lexapro vs Zoloft comparison is that both of the drugs not only are used in the treatment of depression but several other disorders too and in that respect, they are quite different. Zoloft is used in the treatment of depression and obsessive-compulsive disorder, on the other hand, Lexapro vs Zoloft is used in the treatment of the depression and the generalized anxiety disorder.

Zoloft is also used for the treatment of panic disorder, post-traumatic stress disorder, social anxiety disorder and premenstrual dysphoric disorder. The other differences that also supports the Lexapro vs. Zoloft argument is that the strength of the Zoloft tablets is 25 mg, 50 mg, and 100 mg while in oral solution the strength is 25mg/ml and on the other hand the strength of Lexapro tablets are 5, 10 and 20 mg while the oral solution is 1mg/ml. Lexapro versus Zoloft can be used in people that are above 12 years of age while the Zoloft can be used in patients that are above 18 in age.

Cost

The cost difference also helps us with the Lexapro vs Zoloft comparison. The cost of the monthly supply of the Zoloft is $201 while on the other hand the cost of the Lexapro is $180 per month and this shows that cost wise Lexapro is better than the Zoloft but since the cost of these anti-depressant medications is covered by the insurance companies so both are equal cost wise but now you know your priorities even if you don’t have the insurance.

Side effects

The side effects also help us with the Lexapro vs Zoloft comparison and according to it the both of them have same side effects like

Diarrhea

Indigestion

Sexual problems

Sleeping troubles

Anxiety

Seizures

Migraines

Serotonin syndrome

Dizziness etc.

And the only symptom different is constipation that occurs by the use of Lexapro. We should only use one of these two antidepressants at a time because this may lead to interaction like the elevated level of serotonin thus leading to serotonin syndrome.

So this was just an overview of these two drug features and the difference between these two medications will help you understand it better and you should discuss it in detail with your doctor before you start the treatment.

January 30, 2018 2 comments

Depression Health

Lexapro and Alcohol – Effects of Using Them Together

by Healthlinear January 29, 2018

written by Healthlinear

Depression is a very important topic in today’s world because it is increasing among people with every passing day and that’s the reason we are going to discuss Lexapro and Alcohol. And gladly more people are talking about it and addressing it so the awareness can be spread about it. Use of anti-depressants has also been increased a lot due to increased depression but not all the people have the knowledge about how to take their anti-depressants and what things they should do an avoid while taking those medications.

Lexapro is one of the anti-depressants and the use of Lexapro and alcohol will be discussed here so people should know why they should avoid alcohol while they are on the anti-depressants. Anti-depressants are of different types and doctors prescribe it according to the condition of the patients and their other medical history. There is this one class of the anti-depressants that are known a serotonin reuptake inhibitors and they act in such way that they block the uptake of the serotonin which leads to the higher serotonin level.

Serotonin is a chemical that produces the feeling of wellbeing and in an increased level of serotonin, they feeling of wellbeing produces and in this way these medications help with the treatment of depression.

Lexapro

Lexapro is basically the brand name of the drug known as the escitalopram and that drug being the serotonin reuptake inhibitor anti-depressants and they act by balancing the amount of serotonin in the brain that was unbalanced in the state of depression and it is one of the reasons people suffer from depression. Lexapro is also used by adults that are going through anxiety and it is also used for the treatment of some other mental issues.

Most of the people have a fear of taking the medications and for them, it is the safest choice because the SSRI is one of the safest class among the antidepressants which is why they are the first class doctor’s consider while prescribing a patient going through the depression.

Lexapro and Alcohol

Even though the SSRI is the safest class of the anti-depressant drugs but still there are some risks like Lexapro and alcohol because it is probably not the best combination for a person who is going through the major depressive disorder because the drug will be ineffective for the patient and the depression instead of being treated will just get worse and that can lead to the worst consequences and even the life of the patient can be at risk because the number of suicidal attempts due to depression is increasing day by day.

There are some of the drugs that cannot be used together because of their similar effect and the Lexapro and alcohol have the exact same relation to the patient remains untreated even after he is being put on the anti-depressants by the health practitioner or sometimes the condition worsens.

Why alcohol shouldn’t be used with Lexapro

Alcohol with or without in combination of the Lexapro shouldn’t be used in excess and shouldn’t be used in excess at all by the patients with depression. The reason why alcohol shouldn’t be used by the patient if depression is that alcohol depresses the central nervous system and since the patient is already in the depressed state during depression disorder the use of alcohol can worsen the condition of the patient this leading to suicidal thoughts.

The clinical trials show that the Lexapro and alcohol produce almost the same effect and the difference between them is quite low so even if it is to be used by the patient then make sure they don’t drink it in excess or you can be in the danger of some of the serious side effects that you don’t want to deal with in the state of depression.

There is no such way by which treatment can work by switching the antidepressant because almost all the anti-depressants are not suitable to be used with alcohol so you should discuss it thoroughly with the doctor and the best choice is that matter is for how long you are taking anti-depressants you should avoid drinking alcohol.

Effects of using Lexapro and alcohol

Since so far we have developed that Lexapro and alcohol are not the best choices of drugs to be used together and the results of using these drugs together will help you understand the severity of the situation in a better way. To get to better results you should make a comparison of the symptoms that will result from using Lexapro and alcohol versus the healthy, depression-free life. Following are some of the side effects that result from the combined use of the Lexapro and alcohol.

Decreased efficacy of the Lexapro
Alcoholism
Liver problem
Drowsiness
Anxiety
Worsening of depression
Increased intensity of the drug’s side effects like nausea, insomnia, diarrhoea, dry mouth etc.

So this tells us how we should be more concerned about our health and try our best to get out of depression by avoiding completely and if not completely then at least not drinking heavily. The patients who are on the high dose of the anti-depressants like Lexapro should be more careful than those who are still at the initial dosing stages and if you want to get out of depression even faster you should take care of things like this even more. The more you get careless about your depression the closer you are at the risk of suicide so we should try to value our life by taking care of little things like this.

If you think you don’t want to completely quit drinking alcohol then you can discuss your doctor about it. You can drink alcohol from time to time but the heavy drinking can lead to above-mentioned symptoms of the Lexapro and alcohol combined use. But sometimes doctors stop you from alcohol altogether so you must discuss it again with your doctor before having a drink. So this was all you needed to know about the combined use of Lexapro and alcohol and why you shouldn’t take them together.

January 29, 2018 1 comment

Depression Health

Zoloft and Alcohol Combination

by Healthlinear January 27, 2018

written by Healthlinear

Zoloft and Alcohol combination is never a good idea and this whole article is the explanation of all the reasons why these two drugs should not be taken together. Zoloft, as you all know, is a medicine that is prescribed by the health practitioners to the people suffering from depression. Depression is a psychological disorder that has been seeming to be increasing a lot since the past few years and it is most likely to be found among teenager.

Depression is something that keeps eating a person emotionally and most of the people going through it choose to end their life when the depression stays unaddressed so this is why it is important to address the needs of the people around us and in the whole society. Zoloft and other such medications are prescribed by the doctors in the depression but in some situations, even these medications fail to help the person and those such situations include mixing of Zoloft and alcohol.

Symptoms of depression

Depression is a very important issue in today’s society and the more we talk about it the less it is and we as an active member of our society should take part in spreading awareness about depression. Depression is one of the reasons the suicidal ratio increasing day by day.

When you are depressed you lose all the hope in your life and then you see no purpose of your life so you just decide the world is better off without you and this is exactly why we need to fight depression. Depression is most likely to occur in teens as compared to the adults and in females as compared to the males. Following are some of the symptoms of the depression

Helplessness or hopelessness
Changes in appetite and weight
Anger or irritability
Self-loathing and self-destructive attitude
Short attention span
Sleep changes and loss of interest in activities of life.

So these were some of the symptoms and if you see them in yourself then you should definitely visit a doctor.

What is the impact of alcohol and Zoloft in the depression?

Zoloft and Alcohol are two opposite drugs. Alcohol itself is a drug and it is one of those drugs that depress our central nervous system. Even though it activates our nervous system for a little while but then it starts depressing it and if the person is already suffering from the depression you can imagine what the intake of Alcohol can do to them. Zoloft versus Zahra is used as an antidepressant which shows that it has opposite of action.

Zoloft is basically the brand name of the generic drug known as the sertraline. Sertraline is the serotonin reuptake inhibitor and serotonin being a chemical that helps in elevation of your mood upon being blocked from the reuptake can help you get over your depression. So this is how the generic drug sertraline works in the form of capsule Zoloft.

Zoloft and alcohol

Zoloft and Alcohol should not be taken together because both of these drugs are the antagonist of each other. By antagonist to means that action of one drug will be the exact opposite of what other drug is doing and in such way, none of the drugs will be able to produce their action.

Since the situation, we are dealing here is depression we should definitely opt for the drug that helps to recover depression which in this case is Zoloft and not the one that further pulls you in the depression that in this case is the alcohol. The difference between both of these drugs is huge and this is exactly why they are not a perfect combination to be used together.

Drinking while you are in depression will pull you further into it so instead of doing that you should try to get yourself recovered from depression which has the potential to eat up your whole life and your career. If the person is already in a depression and the doctor has prescribed him with the Zoloft then according to U.S Food and Drug Administration guidelines you should not be taking Alcohol at all because then the purpose if your therapy will be futile otherwise.

So due to this type of interaction you should avoid the use of Alcohol at all, in fact, you shouldn’t even look at Alcohol when you already are in the depressed stage because the side effects in such cases are endless and the risk to the life is even greater then.

Interactions

You must have heard of drug-drug interactions. There are two types of drug-drug interaction and that are synergistic or antagonist. Antagonist means the complete opposite of each other and Zoloft and alcohol has that kind of interaction with each other. Alcohol makes the potential side effects of the Zoloft even worse and they are as follows.

Dizziness,
A headache
Depression
Suicidal thoughts
Diarrhea etc.

So these symptoms can get elevated upon the combined use of Zoloft and Alcohol. So while you are on the medications like Zoloft you should avoid drinking beer or any other alcoholic beverages and this isn’t only because alcohol affects the activity of Zoloft it is also because Zoloft makes the effects of Alcohol like drowsiness even worse so you should never consider mixing Zoloft and Alcohol together.

What to do?

What you should do is that you should never mix Zoloft and alcohol as they will alleviate the side effects of each other and if you think you have no control over your drinking then you should probably discuss it through with the doctors so they can suggest you better alternatives and also they can help you with your drinking problem if it’s going out of hand. So now you know how dangerous it is to use the combination of the Zoloft and alcohol and you know how side effects can go even worse and you will then put your own life at the risk and before you know you will be the most depressed person.

January 27, 2018 0 comment

Depression Health

Prozac vs Zoloft : Comparison between Antidepressants

by Healthlinear January 26, 2018

written by Healthlinear

Ever wonder about what antidepressant you should take? There are many, but let’s talk about Prozac vs Zoloft. Prozac and Zoloft both are the antidepressants that are used to treat the depression as well as other conditions like the obsessive-compulsive disorder, anxiety, panic attacks etc. In all such conditions, these antidepressants are prescribed by the doctors. Prozac and Zoloft are the brand names and even though are the antidepressants have different generic drugs.

The generic drug fluoxetine goes by the brand name Prozac and the sertraline hydrochloride is another generic drug that goes by the brand name Zoloft. The end results of both of these drugs are the same but the mechanism of action of Prozac vs. Zoloft is a little different, Prozac’s generic drug is a serotonin reuptake inhibitor it inhibits the serotonin reuptake in such a way that it inhibits the serotonin transporter protein and it’s also a 5HT2C antagonist while the sertraline inhibits the serotonin reuptake by inhibiting the 5HT1A receptor.

Serotonin is basically a chemical in our body that produces the feeling of well-being and happiness so when the serotonin is depleted in our body due to more reuptake it could result in depression, anxiety etc. So when these antidepressants are used they will increase the amount of serotonin in the body by blocking its reuptake and this is how they will help with your mood, good appetite and also balance your sleep.

Depression is a very dangerous disorder and it can have a very negative impact on a person’s life and this is why this disorder must be addressed and medications should be taken as prescribed to reduce and completely eliminate the depression and anxiety from your life.

Features of Prozac and Zoloft

Features of Prozac vs Zoloft will help us understand better which drug is better than the other one and whether your medications need switching or not b the prescriber. Prozac and Zoloft bot is used for the treatment of the obsessive-compulsive disorder OCD and the panic disorder while Prozac only is used for the Bulimia nervosa which is the eating disorder in which the frequent episodes of the binge eating followed by the episodes of trying to lose weight by inducing vomiting.

On the other hand, Zoloft is only used for the post-traumatic stress disorder, premenstrual dysphoric disorder (sudden changes in the mood before menstruation), social anxiety disorder or social phobia. These medications are also used for some other sleeping and eating disorders but these are just some of the off-label uses and these off-label uses are those uses for which the drug can be prescribed by the doctor but it's not the use of the drug was approved by the FDA.

Dosing differences between these two

Prozac was prescribed in the children below 7 years for Obsessive-compulsive disorder and for the rest of the purposes it is prescribed in the adults only and Zoloft is prescribed in the children below 6 years for the OCD and for the other reasons in adults only. Prozac comes in the form of oral capsules of 10mg, 20mg, 40mg and 90mg only Zoloft comes in the form of oral capsules of 25mg, 50mg & 100mg and the oral liquid concentrate solution of 20mg/ml. the good thing that is common about both of these drugs is that patients don’t have to go through the withdrawal upon discontinuing of these medications and also they don’t have the addictive potential for the medication users and this is why people font go through the withdrawal symptoms upon discontinuation. And they both also don’t fall on the list of the controlled substances so there is no potential harm upon the use of these medications.

Side effects

All the medications that we use have some side effects too and there is no medication in the entire world that doesn’t come with a side effect. The side effects caused by both of these drugs are same but there are few side effects that vary in Prozac vs Zoloft. The common side effects that can possibly arise from the usage of these medications are

Nausea and vomiting,
Diarrhea,
Weight gain,
Weight loss,
Insomnia,
A headache,
Dry mouth and
Sexual dysfunctions like the erectile dysfunction.

So these were some of the common side effects while the side effects that we observe in the Prozac vs Zoloft are that Zoloft is most likely to be the reason of diarrhoea than the Prozac so when the patient is undergoing many problems the medical practitioner upon other factors consideration can think about switching to Prozac. Similarly, Prozac versus Zoloft is most likely to be the reason for the dry mouth and the sleep disturbance so in such situations consider switching to the Zoloft to provide the patients maximum comfort. Suicidal thoughts can also initiate in the head of both these substance users between treatments so care should be given to them.

Drug interactions

Drug-drug interactions are a really worse thing so the medical practitioners should check the current medication history of the patient and void prescribing medicines that have a possible interaction with any of the previous medications. The drug-drug interaction of these drugs are with

Monoamine oxidase inhibitor,
Methylene blue injection,
Pimozide,
Linezolid

So make sure to inform the practitioner about your current medications in use. Both of these drugs are also contraindicated in the pregnancy and the breastfeeding stage.

Price variable

The price of both Prozac vs Zoloft varies even though they are used for the same purpose and the price difference is in such a way that the monthly supply of the Prozac is almost $100 more expensive as compared to the Zoloft so when it comes to the pricing Zoloft is better than the Prozac because it is in within the reach of all the classes of society.

Prozac vs Zoloft

Now coming to the final review the Prozac vs Zoloft are better than each other when we are considering only in certain aspects and to check the efficacy of both of them what you need to do is that you can read the reviews of the patients that are already using these medications which will help you to make a better judgment in Prozac vs Zoloft.

January 26, 2018 1 comment