Lexapro Vs Zoloft – A True Comparison

Before discussing Lexapro vs Zoloft, let’s talk about health. Health is a very important aspect of our life and without health, there is no fun in the life. There shouldn’t be any compromise with the health either physical or mental health. To stay healthy we should take part in the healthy activities and stay around the people that are good for the mental health.

But in the today’s world, every person suffering from the health problem wither physical or the mental. The ratio of mental illness is increasing day by day because our attitude towards a healthy life is so negligent and most of the people in the underdeveloped countries don’t even consider the mental health at all and that is why most of such medical problems stay unresolved throughput there life. So this is why there should be more awareness about the mental health so people who are undergoing such sicknesses can seek help.

There are a lot of mental health problems that are found in the society these days land the most common among all of them is the depression. Most of the people in our society due to the burdens of life are going through depression and this ratio is increasing day by day.


Depression is a mental disorder in which our central nervous system becomes depressed and this mental disorder is occurring in a lot of people and the reasons behind this disorder a lot and mostly the current state of our society where everyone is busy doing their own thing and no one have time for each other and in this mad race of being better most of the people are suffering from depression. The symptoms of depression can help us realize the problem in the very early stage but the problem is that most people pay no attention to these signs and symptoms and some of them even don’t know the signs and symptoms. Following are the symptoms of the depression.

  • Anger
  • Sleep changes
  • Loss of energy
  • Loss of interest
  • Concentration problem
  • Weight loss
  • Self-loathing etc.

concentration Problems

So these were some of the symptoms that are found in the people that are suffering from the depression. Depression must be diagnosed because in most of the people depression leads to that stage where they start considering suicide and most of the people even opt for the suicide. The studies have shown that depression is more common among the teenagers as compared to the adults and gender-wise it is more common among the women as compared to the men.

Treatment of depression

A lot of drugs are suggested for the treatment of depression by now and Lexapro and Zoloft are among those drugs. Both of the drugs are used for the treatment of depression which is why we will further discuss the Lexapro vs Zoloft comparison to help you understand which one is best for you in the case of depression. Lexapro is an antidepressant that contains the drug escitalopram and Zoloft is the anti-depressant that contains the drug known as sertraline.

The Lexapro vs Zoloft comparison will help us understand the difference between these two drugs and will help us make the better decision. The escitalopram is a serotonin reuptake inhibitor and the sertraline is same too and the fact they both are the selective serotonin reuptake inhibitor they are considered the exact same but it’s not the way it is.

The SSRI drugs act in such a way that they inhibit the reuptake of serotonin thus increasing the amount of serotonin in the brain and serotonin is the chemical that lightens the mood of a person and this help with the treatment of depression. In depression, the level of serotonin gets unbalances and these two drugs help in the balancing of this chemical in the brain. These drugs are similar too but there are also some differences that support the Lexapro vs Zoloft argument.

Lexapro vs Zoloft

The first thing that we should know in the Lexapro vs Zoloft comparison is that both of the drugs not only are used in the treatment of depression but several other disorders too and in that respect, they are quite different. Zoloft is used in the treatment of depression and obsessive-compulsive disorder, on the other hand, Lexapro vs Zoloft is used in the treatment of the depression and the generalized anxiety disorder.

Zoloft is also used for the treatment of panic disorder, post-traumatic stress disorder, social anxiety disorder and premenstrual dysphoric disorder. The other differences that also supports the Lexapro vs. Zoloft argument is that the strength of the Zoloft tablets is 25 mg, 50 mg, and 100 mg while in oral solution the strength is 25mg/ml and on the other hand the strength of Lexapro tablets are 5, 10 and 20 mg while the oral solution is 1mg/ml. Lexapro versus Zoloft can be used in people that are above 12 years of age while the Zoloft can be used in patients that are above 18 in age.


The cost difference also helps us with the Lexapro vs Zoloft comparison. The cost of the monthly supply of the Zoloft is $201 while on the other hand the cost of the Lexapro is $180 per month and this shows that cost wise Lexapro is better than the Zoloft but since the cost of these anti-depressant medications is covered by the insurance companies so both are equal cost wise but now you know your priorities even if you don’t have the insurance.

Side effects

The side effects also help us with the Lexapro vs Zoloft comparison and according to it the both of them have same side effects like



Sexual problems

Sleeping troubles




Serotonin syndrome

Dizziness etc.

And the only symptom different is constipation that occurs by the use of Lexapro. We should only use one of these two antidepressants at a time because this may lead to interaction like the elevated level of serotonin thus leading to serotonin syndrome.

So this was just an overview of these two drug features and the difference between these two medications will help you understand it better and you should discuss it in detail with your doctor before you start the treatment.

2 thoughts on “Lexapro Vs Zoloft – A True Comparison”

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