Loperamide: Uses, Mechanism of Action and Warnings

What is Loperamide? Used to treat non-specific diarrhea, Loperamide; an anti-diarrheal long-acting drug is also a suitable candidate for the treatment of Chronic diarrhea or gastroenteritis. It is an OTC (over-the-counter) oral anti-diarrheal medication that was initially introduced in 1969. It was first used medically in 1976 and became available as a non-prescription medicine in […]

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Akineton: Uses, Dosage, Indications, and Side Effects

Dosage form: Oral tablets (Prolonged-release) 4mg, 2mg Active ingredient: Biperiden hydrochloride What is Akineton used for? A prescription-only drug Akineton; is primarily used to treat all forms of Parkinson’s disease. Other therapeutic indications include Drug-induced extrapyramidal symptoms Excito-motor phenomena Akinesia Rigidity Akathisia Acute dystonia Akineton is also available in 5mg/ml ampules. Contraindications Hypersensitivity Narrow-angle glaucoma […]

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Biperiden: Uses, Side Effects and Mechanism of Action

What is Biperiden? A cholinergic antagonist drug biperiden is used to treat Parkinsonism. Biperiden Hydrochloride Biperiden Hydrochloride is the salt from the drug Biperiden. Tablet dosage forms of it include the drug in this chemical form. A central and peripheral nerve system muscarinic antagonist. Arteriosclerotic, idiopathic, and postencephalitic parkinsonism have all been treated with it. […]

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Mesna (chemoprotectant): Contraindications, Side Effects, Uses, and Brand Names

A synthetic sulfhydryl compound Mesna; is a chemo-protective agent used to prevent ifosfamide-induced hemorrhagic cystitis. It can be given intravenously or orally. The drug is rapidly oxidized to mesna disulfide, which is its main metabolite (dimesna). In the kidney, dimesna is reduced to a free thiol, which interacts with ifosfamide metabolites and causes their detoxification. […]

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Nebupent: Active ingredient, Mechanism of Action, and Indications

What is NebuPent NebuPent contains Pentamidine which is an anti-infective agent. It is a prescription-only drug. NubePent Active Ingredient Pentamidine isethionate How do you take NebuPent? / How do you administer NebuPent? Only for Oral Inhalation For the prevention of Pneumocystis jiroveci pneumonia, an adult should take 300 mg of NebuPent once every four weeks […]

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Pentamidine: Uses, Mechanism of Action, Side Effects, and Contraindications

What is Pentamidine? The drug Pentamidine is broadly classified under anti-protozoal drugs. Several diamidine compounds have trypanocidal action, including pentamidine. In the treatment of visceral leishmaniasis, pentamidine isethionate is utilized instead of sodium stibogluconate. It can also be used to treat early trypanosomiasis. Pentamidine Mechanism of Action The precise mechanism has yet to be discovered. […]

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Eflornithine: Mechanism of Action, Uses, Side effects, and Contraindications

Difluoromethylornithine DFMO which is now commonly known as Eflornithine shows clinical efficacy against Pneumocystis pneumonia (PCP) and West African trypanosomiasis. The drug was initially designed to be used as an anticancer agent, but it proved to be unproductive later. African sleeping sickness, which is also known as Human African trypanosomiasis, is a parasite infection transmitted […]

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